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Modulation of MicroRNA-194 and Cell Migration by HER2-Targeting Trastuzumab in Breast Cancer

Trastuzumab, a humanized monoclonal antibody directed against the extracellular domain of the HER2 oncoprotein, can effectively target HER2-positive breast cancer through several mechanisms. Although the effects of trastuzumab on cancer cell proliferation, angiogenesis and apoptosis have been invest...

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Detalles Bibliográficos
Autores principales: Le, Xiao-Feng, Almeida, Maria I., Mao, Weiqun, Spizzo, Riccardo, Rossi, Simona, Nicoloso, Milena S., Zhang, Shu, Wu, Yun, Calin, George A., Bast, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400637/
https://www.ncbi.nlm.nih.gov/pubmed/22829924
http://dx.doi.org/10.1371/journal.pone.0041170