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A Functional +61G/A Polymorphism in Epidermal Growth Factor Is Associated with Glioma Risk among Asians

BACKGROUND: Epidermal growth factor (EGF), a potent mitogenic protein, plays an important role in the development of cancers, including glioma. Previous studies showed that the EGF +61G/A polymorphism (rs4444903) may lead to an alteration in EGF production and/or activity, which can result in indivi...

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Detalles Bibliográficos
Autores principales: Xu, Xin, Xi, Lei, Zeng, Jie, Yao, Qinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400669/
https://www.ncbi.nlm.nih.gov/pubmed/22829952
http://dx.doi.org/10.1371/journal.pone.0041470