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Autism-Relevant Social Abnormalities and Cognitive Deficits in Engrailed-2 Knockout Mice

ENGRAILED 2 (En2), a homeobox transcription factor, functions as a patterning gene in the early development and connectivity of rodent hindbrain and cerebellum, and regulates neurogenesis and development of monoaminergic pathways. To further understand the neurobiological functions of En2, we conduc...

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Detalles Bibliográficos
Autores principales: Brielmaier, Jennifer, Matteson, Paul G., Silverman, Jill L., Senerth, Julia M., Kelly, Samantha, Genestine, Matthieu, Millonig, James H., DiCicco-Bloom, Emanuel, Crawley, Jacqueline N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400671/
https://www.ncbi.nlm.nih.gov/pubmed/22829897
http://dx.doi.org/10.1371/journal.pone.0040914