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Autism-Relevant Social Abnormalities and Cognitive Deficits in Engrailed-2 Knockout Mice
ENGRAILED 2 (En2), a homeobox transcription factor, functions as a patterning gene in the early development and connectivity of rodent hindbrain and cerebellum, and regulates neurogenesis and development of monoaminergic pathways. To further understand the neurobiological functions of En2, we conduc...
Autores principales: | Brielmaier, Jennifer, Matteson, Paul G., Silverman, Jill L., Senerth, Julia M., Kelly, Samantha, Genestine, Matthieu, Millonig, James H., DiCicco-Bloom, Emanuel, Crawley, Jacqueline N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400671/ https://www.ncbi.nlm.nih.gov/pubmed/22829897 http://dx.doi.org/10.1371/journal.pone.0040914 |
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