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Concomitant administration of simvastatin with ivabradine in contrast to metoprolol intensifies slowing of heart rate in normo- and hypercholesterolemic rats
INTRODUCTION: β-Blockers play a significant role in therapeutic heart rate (HR) management and angina control. In patients who are unable to tolerate β-blockers ivabradine could be particularly useful. The aim of the study was to establish whether concomitant administration of simvastatin with ivabr...
Autores principales: | Owczarek, Jacek, Jasińska, Magdalena, Drożdż, Jarosław, Orszulak-Michalak, Daria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400921/ https://www.ncbi.nlm.nih.gov/pubmed/22852014 http://dx.doi.org/10.5114/aoms.2012.29411 |
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