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A Bayesian analysis of the chromosome architecture of human disorders by integrating reductionist data

In this paper, we present a Bayesian approach to estimate a chromosome and a disorder network from the Online Mendelian Inheritance in Man (OMIM) database. In contrast to other approaches, we obtain statistic rather than deterministic networks enabling a parametric control in the uncertainty of the...

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Detalles Bibliográficos
Autores principales: Emmert-Streib, Frank, de Matos Simoes, Ricardo, Tripathi, Shailesh, Glazko, Galina V., Dehmer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400933/
https://www.ncbi.nlm.nih.gov/pubmed/22822426
http://dx.doi.org/10.1038/srep00513