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A Bayesian analysis of the chromosome architecture of human disorders by integrating reductionist data
In this paper, we present a Bayesian approach to estimate a chromosome and a disorder network from the Online Mendelian Inheritance in Man (OMIM) database. In contrast to other approaches, we obtain statistic rather than deterministic networks enabling a parametric control in the uncertainty of the...
Autores principales: | Emmert-Streib, Frank, de Matos Simoes, Ricardo, Tripathi, Shailesh, Glazko, Galina V., Dehmer, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400933/ https://www.ncbi.nlm.nih.gov/pubmed/22822426 http://dx.doi.org/10.1038/srep00513 |
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