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Gowinda: unbiased analysis of gene set enrichment for genome-wide association studies

Summary: An analysis of gene set [e.g. Gene Ontology (GO)] enrichment assumes that all genes are sampled independently from each other with the same probability. These assumptions are violated in genome-wide association (GWA) studies since (i) longer genes typically have more single-nucleotide polym...

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Detalles Bibliográficos
Autores principales: Kofler, Robert, Schlötterer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400962/
https://www.ncbi.nlm.nih.gov/pubmed/22635606
http://dx.doi.org/10.1093/bioinformatics/bts315