Platelet-Derived Toll-Like Receptor 4 (Tlr-4) Is Sufficient to Promote Microvascular Thrombosis in Endotoxemia

Endotoxin (lipopolysaccharide, LPS) produced by gram-negative bacteria initiates a host of pro-inflammatory effects through Toll-like receptor 4 (TLR-4). We reported previously that LPS enhances microvascular thrombosis in cremaster venules of wild-type mice, but had no effect in mice deficient in T...

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Detalles Bibliográficos
Autores principales: Stark, Ryan J., Aghakasiri, Niloufar, Rumbaut, Rolando E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401143/
https://www.ncbi.nlm.nih.gov/pubmed/22911769
http://dx.doi.org/10.1371/journal.pone.0041254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401143/
https://www.ncbi.nlm.nih.gov/pubmed/22911769
http://dx.doi.org/10.1371/journal.pone.0041254

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