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Mechanism of Cullin3 E3 Ubiquitin Ligase Dimerization
Cullin E3 ligases are the largest family of ubiquitin ligases with diverse cellular functions. One of seven cullin proteins serves as a scaffold protein for the assembly of the multisubunit ubiquitin ligase complex. Cullin binds the RING domain protein Rbx1/Rbx2 via its C-terminus and a cullin-speci...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401178/ https://www.ncbi.nlm.nih.gov/pubmed/22911784 http://dx.doi.org/10.1371/journal.pone.0041350 |