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Restoration of Dioxin-Induced Damage to Fetal Steroidogenesis and Gonadotropin Formation by Maternal Co-Treatment with α-Lipoic Acid

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), an endocrine disruptor, causes reproductive and developmental toxic effects in pups following maternal exposure in a number of animal models. Our previous studies have demonstrated that TCDD imprints sexual immaturity by suppressing the expression of fetal...

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Detalles Bibliográficos
Autores principales: Koga, Takayuki, Ishida, Takumi, Takeda, Tomoki, Ishii, Yuji, Uchi, Hiroshi, Tsukimori, Kiyomi, Yamamoto, Midori, Himeno, Masaru, Furue, Masutaka, Yamada, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401201/
https://www.ncbi.nlm.nih.gov/pubmed/22911699
http://dx.doi.org/10.1371/journal.pone.0040322