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The Crystal Structures of Dystrophin and Utrophin Spectrin Repeats: Implications for Domain Boundaries

Dystrophin and utrophin link the F-actin cytoskeleton to the cell membrane via an associated glycoprotein complex. This functionality results from their domain organization having an N-terminal actin-binding domain followed by multiple spectrin-repeat domains and then C-terminal protein-binding moti...

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Detalles Bibliográficos
Autores principales: Muthu, Muralidharan, Richardson, Kylie A., Sutherland-Smith, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401230/
https://www.ncbi.nlm.nih.gov/pubmed/22911693
http://dx.doi.org/10.1371/journal.pone.0040066