Influence of sildenafil on the anticonvulsant action of selected antiepileptic drugs against pentylenetetrazole-induced clonic seizures in mice

The aim of the present study was to investigate the effect of sildenafil, a selective phosphodiesterase 5 (PDE5) inhibitor, on threshold for clonic seizures in mice. In addition, the effects of sildenafil on the anticonvulsant activity of selected antiepileptic drugs (AEDs), i.e., clonazepam (CZP),...

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Detalles Bibliográficos
Autores principales: Nieoczym, Dorota, Socała, Katarzyna, Łuszczki, Jarogniew J., Czuczwar, Stanisław J., Wlaź, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2012
Materias:
Basic Neurosciences, Genetics and Immunology - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401299/
https://www.ncbi.nlm.nih.gov/pubmed/22315091
http://dx.doi.org/10.1007/s00702-012-0767-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401299/
https://www.ncbi.nlm.nih.gov/pubmed/22315091
http://dx.doi.org/10.1007/s00702-012-0767-1

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