The angiogenic inhibitor TNP-470 decreases caloric intake and weight gain in high fat fed mice

The angiogenic inhibitor TNP-470 attenuates high fat diet induced obesity; however, it is not clear how the compound alters energy balance to prevent weight gain. Five week old C57Bl/6J mice were fed high-fat diet (45% energy from fat) for 6.5 weeks and treated with TNP-470 (20 mg/kg body weight; n=...

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Detalles Bibliográficos
Autores principales: White, Heather M., Acton, Anthony J., Considine, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401363/
https://www.ncbi.nlm.nih.gov/pubmed/22510957
http://dx.doi.org/10.1038/oby.2012.87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401363/
https://www.ncbi.nlm.nih.gov/pubmed/22510957
http://dx.doi.org/10.1038/oby.2012.87

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