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The angiogenic inhibitor TNP-470 decreases caloric intake and weight gain in high fat fed mice
The angiogenic inhibitor TNP-470 attenuates high fat diet induced obesity; however, it is not clear how the compound alters energy balance to prevent weight gain. Five week old C57Bl/6J mice were fed high-fat diet (45% energy from fat) for 6.5 weeks and treated with TNP-470 (20 mg/kg body weight; n=...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401363/ https://www.ncbi.nlm.nih.gov/pubmed/22510957 http://dx.doi.org/10.1038/oby.2012.87 |