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M6P/IGF2R modulates the invasiveness of liver cells via its capacity to bind mannose 6-phosphate residues
BACKGROUND & AIMS: The mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R), a multifunctional protein, plays a central role in intracellular targeting of lysosomal enzymes and control of insulin-like growth factor II (IGF-II) bioactivity. Importantly, the gene encoding this re...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401376/ https://www.ncbi.nlm.nih.gov/pubmed/22521359 http://dx.doi.org/10.1016/j.jhep.2012.03.026 |