Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity

The active form of Escherichia coli DNA polymerase V responsible for damage-induced mutagenesis is a multiprotein complex (UmuD′(2)C-RecA-ATP), called pol V Mut. Optimal activity of pol V Mut in vitro is observed on an SSB-coated single-stranded circular DNA template in the presence of the β/γ compl...

Descripción completa

Detalles Bibliográficos
Autores principales: Vaisman, Alexandra, Kuban, Wojciech, McDonald, John P., Karata, Kiyonobu, Yang, Wei, Goodman, Myron F., Woodgate, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401427/
https://www.ncbi.nlm.nih.gov/pubmed/22422840
http://dx.doi.org/10.1093/nar/gks233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401427/
https://www.ncbi.nlm.nih.gov/pubmed/22422840
http://dx.doi.org/10.1093/nar/gks233

Ejemplares similares