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The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP

The homologous cellular coactivators p300 and CBP contain intrinsic lysine acetyl transferase (termed HAT) activity. This activity is responsible for acetylation of several sites on the histones as well as modification of transcription factors. In a previous study, we found that HBZ, encoded by the...

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Detalles Bibliográficos
Autores principales: Wurm, Torsten, Wright, Diana G., Polakowski, Nicholas, Mesnard, Jean-Michel, Lemasson, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401433/
https://www.ncbi.nlm.nih.gov/pubmed/22434882
http://dx.doi.org/10.1093/nar/gks244