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The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP
The homologous cellular coactivators p300 and CBP contain intrinsic lysine acetyl transferase (termed HAT) activity. This activity is responsible for acetylation of several sites on the histones as well as modification of transcription factors. In a previous study, we found that HBZ, encoded by the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401433/ https://www.ncbi.nlm.nih.gov/pubmed/22434882 http://dx.doi.org/10.1093/nar/gks244 |