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Mutually exclusive splicing regulates the Na(v) 1.6 sodium channel function through a combinatorial mechanism that involves three distinct splicing regulatory elements and their ligands

Mutually exclusive splicing is a form of alternative pre-mRNA processing that consists in the use of only one of a set of two or more exons. We have investigated the mechanisms involved in this process for exon 18 of the Na(v) 1.6 sodium channel transcript and its significance regarding gene-express...

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Detalles Bibliográficos
Autores principales: Zubović, Lorena, Baralle, Marco, Baralle, Francisco E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401437/
https://www.ncbi.nlm.nih.gov/pubmed/22434879
http://dx.doi.org/10.1093/nar/gks249