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Yields of damage to C4′ deoxyribose and to pyrimidines in pUC18 by the direct effect of ionizing radiation

Our mechanistic understanding of damage formation in DNA by the direct effect relies heavily on what is known of free radical intermediates studied by EPR spectroscopy. Bridging this information to stable product formation requires methods with comparable sensitivities, a criterion met by the (32)P-...

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Detalles Bibliográficos
Autores principales: Peoples, Anita R., Lee, Jane, Weinfeld, Michael, Milligan, Jamie R., Bernhard, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401456/
https://www.ncbi.nlm.nih.gov/pubmed/22467205
http://dx.doi.org/10.1093/nar/gks271