A mostly traditional approach improves alignment of bisulfite-converted DNA

Cytosines in genomic DNA are sometimes methylated. This affects many biological processes and diseases. The standard way of measuring methylation is to use bisulfite, which converts unmethylated cytosines to thymines, then sequence the DNA and compare it to a reference genome sequence. We describe a...

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Detalles Bibliográficos
Autores principales: Frith, Martin C., Mori, Ryota, Asai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401460/
https://www.ncbi.nlm.nih.gov/pubmed/22457070
http://dx.doi.org/10.1093/nar/gks275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401460/
https://www.ncbi.nlm.nih.gov/pubmed/22457070
http://dx.doi.org/10.1093/nar/gks275

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