The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase

Eukaryotic translation initiation is a highly regulated process in protein synthesis. The principal translation initiation factor eIF4AI displays helicase activity, unwinding secondary structures in the mRNAs 5′-UTR. Single molecule fluorescence resonance energy transfer (sm-FRET) is applied here to...

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Detalles Bibliográficos
Autores principales: Sun, Yingjie, Atas, Evrim, Lindqvist, Lisa, Sonenberg, Nahum, Pelletier, Jerry, Meller, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401463/
https://www.ncbi.nlm.nih.gov/pubmed/22457067
http://dx.doi.org/10.1093/nar/gks278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401463/
https://www.ncbi.nlm.nih.gov/pubmed/22457067
http://dx.doi.org/10.1093/nar/gks278

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