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The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase

Eukaryotic translation initiation is a highly regulated process in protein synthesis. The principal translation initiation factor eIF4AI displays helicase activity, unwinding secondary structures in the mRNAs 5′-UTR. Single molecule fluorescence resonance energy transfer (sm-FRET) is applied here to...

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Detalles Bibliográficos
Autores principales:	Sun, Yingjie, Atas, Evrim, Lindqvist, Lisa, Sonenberg, Nahum, Pelletier, Jerry, Meller, Amit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401463/ https://www.ncbi.nlm.nih.gov/pubmed/22457067 http://dx.doi.org/10.1093/nar/gks278

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