Fluorescence-based incision assay for human XPF–ERCC1 activity identifies important elements of DNA junction recognition

The structure-specific endonuclease activity of the human XPF–ERCC1 complex is essential for a number of DNA processing mechanisms that help to maintain genomic integrity. XPF–ERCC1 cleaves DNA structures such as stem–loops, bubbles or flaps in one strand of a duplex where there is at least one down...

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Detalles Bibliográficos
Autores principales: Bowles, Maureen, Lally, John, Fadden, Andrew J., Mouilleron, Stephane, Hammonds, Timothy, McDonald, Neil Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401468/
https://www.ncbi.nlm.nih.gov/pubmed/22457069
http://dx.doi.org/10.1093/nar/gks284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401468/
https://www.ncbi.nlm.nih.gov/pubmed/22457069
http://dx.doi.org/10.1093/nar/gks284

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