Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene

The MYB proto-oncogene is expressed in most estrogen receptor-positive (ERα(+)) breast tumors and cell lines. Expression of MYB is controlled, in breast cancer and other cell types, by a transcriptional pausing mechanism involving an attenuation site located ∼1.7 kb downstream from the transcription...

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Detalles Bibliográficos
Autores principales: Mitra, Partha, Pereira, Lloyd A., Drabsch, Yvette, Ramsay, Robert G., Gonda, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401469/
https://www.ncbi.nlm.nih.gov/pubmed/22492511
http://dx.doi.org/10.1093/nar/gks286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401469/
https://www.ncbi.nlm.nih.gov/pubmed/22492511
http://dx.doi.org/10.1093/nar/gks286

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