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Loading mechanisms of ring helicases at replication origins

Threading of DNA through the central channel of a replicative ring helicase is known as helicase loading, and is a pivotal event during replication initiation at replication origins. Once loaded, the helicase recruits the primase through a direct protein–protein interaction to complete the initial ‘...

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Detalles Bibliográficos
Autor principal: Soultanas, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401641/
https://www.ncbi.nlm.nih.gov/pubmed/22417087
http://dx.doi.org/10.1111/j.1365-2958.2012.08012.x