Cargando…

Group V phospholipase A(2) increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane

Acute lung injury (ALI) is characterized by inflammatory disruption of the alveolar–vascular barrier, resulting in severe respiratory compromise. Inhibition of the intercellular messenger protein, Group V phospholipase A(2) (gVPLA(2)), blocks vascular permeability caused by LPS both in vivo and in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Muñoz, Nilda M., Desai, Anjali, Meliton, Lucille N., Meliton, Angelo Y., Zhou, Tingting, Leff, Alan R., Dudek, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401872/
https://www.ncbi.nlm.nih.gov/pubmed/22837859
http://dx.doi.org/10.4103/2045-8932.97604