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Activation of the unfolded protein response is associated with pulmonary hypertension

Pulmonary hypertension remains an important cause of morbidity and mortality. Although there is currently no cure, descriptions of defective intracellular trafficking and protein misfolding in vascular cell models of pulmonary hypertension have been recently reported. We tested the hypothesis that a...

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Detalles Bibliográficos
Autores principales: Yeager, Michael E., Reddy, Monica B., Nguyen, Cecilia M., Colvin, Kelley L., Ivy, D. Dunbar, Stenmark, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401877/
https://www.ncbi.nlm.nih.gov/pubmed/22837864
http://dx.doi.org/10.4103/2045-8932.97613