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NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation
BACKGROUND: Advanced mast cell (MC) disorders are characterized by uncontrolled growth of neoplastic MC in various organs, mediator-related symptoms, and a poor prognosis. Kit mutations supposedly contribute to abnormal growth and drug resistance in these patients. METHODS: We established a novel ca...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401908/ https://www.ncbi.nlm.nih.gov/pubmed/22583069 http://dx.doi.org/10.1111/j.1398-9995.2012.02833.x |