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Age and Geographical Distribution in Families with BRCA1/BRCA2 Mutations in the Slovak Republic

Molecular diagnostics of hereditary breast and/or ovarian cancer is mainly based on detection of BRCA1 and BRCA2 germline mutations in suspected families. The aim of the study was to determine the frequency, age and geographical distribution in 130 Slovak hereditary breast and ovarian cancer (HBOC)...

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Detalles Bibliográficos
Autores principales: Ciernikova, Sona, Tomka, Miroslav, Kovac, Michal, Stevurkova, Viola, Zajac, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401926/
https://www.ncbi.nlm.nih.gov/pubmed/20223009
http://dx.doi.org/10.1186/1897-4287-4-1-7