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BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues

The concept of oligomerization of G protein-coupled receptor (GPCR) opens new perspectives regarding physiological function regulation. The capacity of one GPCR to modify its binding and coupling properties by interacting with a second one can be at the origin of regulations unsuspected two decades...

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Detalles Bibliográficos
Autores principales: Cottet, Martin, Faklaris, Orestis, Maurel, Damien, Scholler, Pauline, Doumazane, Etienne, Trinquet, Eric, Pin, Jean-Philippe, Durroux, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401989/
https://www.ncbi.nlm.nih.gov/pubmed/22837753
http://dx.doi.org/10.3389/fendo.2012.00092