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Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice
The identification of susceptibility genes for human disease is a major goal of current biomedical research. Both sequence and structural variation have emerged as major genetic sources of phenotypic variability and growing evidence points to copy number variation as a particularly important source...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402001/ https://www.ncbi.nlm.nih.gov/pubmed/21204268 http://dx.doi.org/10.1002/emmm.201000112 |