Nesfatin-1 Action in the Brain Increases Insulin Sensitivity Through Akt/AMPK/TORC2 Pathway in Diet-Induced Insulin Resistance

Nesfatin-1, derived from nucleobindin 2, was recently identified as an anorexigenic signal peptide. However, its neural role in glucose homeostasis and insulin sensitivity is unknown. To evaluate the metabolic impact and underlying mechanisms of central nesfatin-1 signaling, we infused nesfatin-1 in...

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Detalles Bibliográficos
Autores principales: Yang, Mengliu, Zhang, Zhihong, Wang, Chong, Li, Ke, Li, Shengbing, Boden, Guenther, Li, Ling, Yang, Gangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402309/
https://www.ncbi.nlm.nih.gov/pubmed/22688332
http://dx.doi.org/10.2337/db11-1755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402309/
https://www.ncbi.nlm.nih.gov/pubmed/22688332
http://dx.doi.org/10.2337/db11-1755

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