Methazolamide Is a New Hepatic Insulin Sensitizer That Lowers Blood Glucose In Vivo

We previously used Gene Expression Signature technology to identify methazolamide (MTZ) and related compounds with insulin sensitizing activity in vitro. The effects of these compounds were investigated in diabetic db/db mice, insulin-resistant diet-induced obese (DIO) mice, and rats with streptozot...

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Detalles Bibliográficos
Autores principales: Konstantopoulos, Nicky, Molero, Juan C., McGee, Sean L., Spolding, Briana, Connor, Tim, de Vries, Melissa, Wanyonyi, Stephen, Fahey, Richard, Morrison, Shona, Swinton, Courtney, Jones, Sharon, Cooper, Adrian, Garcia-Guerra, Lucia, Foletta, Victoria C., Krippner, Guy, Andrikopoulos, Sofianos, Walder, Ken R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402314/
https://www.ncbi.nlm.nih.gov/pubmed/22586591
http://dx.doi.org/10.2337/db11-0578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402314/
https://www.ncbi.nlm.nih.gov/pubmed/22586591
http://dx.doi.org/10.2337/db11-0578

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