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A Novel Anti-inflammatory Role for Spleen-Derived Interleukin-10 in Obesity-Induced Inflammation in White Adipose Tissue and Liver

Obesity is associated with systemic low-grade inflammation and obesity-related metabolic disorders. Considering that obesity decreases the expression of proinflammatory cytokines in the spleen, we assessed the role of interleukin (IL)-10, an anti-inflammatory cytokine produced by the spleen, in the...

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Detalles Bibliográficos
Autores principales: Gotoh, Koro, Inoue, Megumi, Masaki, Takayuki, Chiba, Seiichi, Shimasaki, Takanobu, Ando, Hisae, Fujiwara, Kansuke, Katsuragi, Isao, Kakuma, Tetsuya, Seike, Masataka, Sakata, Toshiie, Yoshimatsu, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402315/
https://www.ncbi.nlm.nih.gov/pubmed/22648387
http://dx.doi.org/10.2337/db11-1688