Promoter DNA Methylation Regulates Murine SUR1 (Abcc8) and SUR2 (Abcc9) Expression in HL-1 Cardiomyocytes

Two mammalian genes encode the SURx (SUR1, Abcc8 and SUR2, Abcc9) subunits that combine with Kir6.2 (Kcnj11) subunits to form the ATP-sensitive potassium (KATP) channel in cardiac myocytes. Different isoform combinations endow the channel with distinct physiological and pharmacological properties, a...

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Detalles Bibliográficos
Autores principales: Fatima, Naheed, Schooley, James F., Claycomb, Willliam C., Flagg, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402388/
https://www.ncbi.nlm.nih.gov/pubmed/22844491
http://dx.doi.org/10.1371/journal.pone.0041533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402388/
https://www.ncbi.nlm.nih.gov/pubmed/22844491
http://dx.doi.org/10.1371/journal.pone.0041533

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