Cargando…

Promoter DNA Methylation Regulates Murine SUR1 (Abcc8) and SUR2 (Abcc9) Expression in HL-1 Cardiomyocytes

Two mammalian genes encode the SURx (SUR1, Abcc8 and SUR2, Abcc9) subunits that combine with Kir6.2 (Kcnj11) subunits to form the ATP-sensitive potassium (KATP) channel in cardiac myocytes. Different isoform combinations endow the channel with distinct physiological and pharmacological properties, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fatima, Naheed, Schooley, James F., Claycomb, Willliam C., Flagg, Thomas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402388/ https://www.ncbi.nlm.nih.gov/pubmed/22844491 http://dx.doi.org/10.1371/journal.pone.0041533

Ejemplares similares

Targeting SUR1/Abcc8-Type Neuroendocrine K(ATP) Channels in Pancreatic Islet Cells
por: Nakamura, Yumiko, et al.
Publicado: (2014)

Neonatal Diabetes and Congenital Hyperinsulinism Caused by Mutations in ABCC8/SUR1 are Associated with Altered and Opposite Affinities for ATP and ADP
por: Ortiz, David, et al.
Publicado: (2015)

Incretin Effect of Glucagon-Like Peptide 1 Receptor Agonist Is Preserved in Presence of ABCC8/SUR1 Mutation in β-Cell
por: Bourron, Olivier, et al.
Publicado: (2012)

Histone deacetylase inhibitors modulate K(ATP) subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis
por: Fatima, Naheed, et al.
Publicado: (2015)

ABCC9 Is Downregulated and Prone to Microsatellite Instability on ABCC9tetra in Canine Breast Cancer
por: Hao, Pan, et al.
Publicado: (2022)

Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis
por: Makar, Tapas K., et al.
Publicado: (2015)

The Common C49620T Polymorphism in the Sulfonylurea Receptor Gene SUR1 (ABCC8) in Patients with Gestational Diabetes and Subsequent Glucose Metabolism Abnormalities
por: Molęda, Piotr, et al.
Publicado: (2012)

Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the K(ATP) channel
por: Cooper, Paige E., et al.
Publicado: (2015)

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines
por: Low, Floren G., et al.
Publicado: (2020)

Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma
por: Bagnoli, Marina, et al.
Publicado: (2013)

ABCC9-related Intellectual disability Myopathy Syndrome is a K(ATP) channelopathy with loss-of-function mutations in ABCC9
por: Smeland, Marie F., et al.
Publicado: (2019)

Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo
por: Hill, Christopher R., et al.
Publicado: (2013)

Neonatal Hypoglycaemia due to ABCC8 Gene Mutation
por: Kumar, Ashok, et al.
Publicado: (2020)

Bixin and Fuxoxanthin Alone and in Combination with Cisplatin Regulate ABCC1 and ABCC2 Transcription in A549 Lung Cancer Cells
por: Chandra, Ferdy, et al.
Publicado: (2023)

Overexpression of ABCC1 Confers Drug Resistance to Betulin
por: Chen, Xuan-Yu, et al.
Publicado: (2021)

Correspondence to ‘Neonatal hypoglycaemia due to ABCC8 gene mutation’
por: Maralihalli, Mahesh
Publicado: (2021)

Case report: Congenital hyperinsulinemia with ABCC8 gene mutations
por: Zhang, Jin, et al.
Publicado: (2022)

Neonatal hyperinsulinism with an ABCC8 mutation: A case report
por: Liu, Meng-Tong, et al.
Publicado: (2023)

In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs
por: Borel, Florie, et al.
Publicado: (2011)

Comparative Molecular Docking Studies with ABCC1 and Aquaporin 9 in the Arsenite Complex Efflux
por: Poojan, Shiv, et al.
Publicado: (2014)

ABCC8-Related Monogenic Diabetes Presenting Like Type 1 Diabetes in an Adolescent
por: Grier, Alexandra E., et al.
Publicado: (2023)

Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression
por: Stojic, Jelena, et al.
Publicado: (2007)

Overexpression of MRP1/ABCC1, Survivin and BCRP/ABCC2 Predicts the Resistance of Diffuse Large B-Cell Lymphoma to R-CHOP Treatment
por: Mandić, Danijela, et al.
Publicado: (2023)

Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma
por: Ruiz-López, Eduardo, et al.
Publicado: (2022)

Paternally inherited ABCC8 mutation causing diffuse congenital hyperinsulinism
por: Chandran, Suresh, et al.
Publicado: (2013)

Diazoxide-unresponsive congenital hyperinsulinism associated with ABCC8 nonsense mutation
por: Hussain, Suhaimi, et al.
Publicado: (2015)

Genome-edited zebrafish model of ABCC8 loss-of-function disease
por: Ikle, Jennifer M., et al.
Publicado: (2022)

ABCC6 Mutation in Patients with Angioid Streaks
por: Mizutani, Yoshihiro, et al.
Publicado: (2006)

Is ABCC6 a genuine mitochondrial protein?
por: Ferré, Marc, et al.
Publicado: (2013)

ABCC6 deficiency promotes dyslipidemia and atherosclerosis
por: Brampton, Christopher, et al.
Publicado: (2021)

Copy number variation in the ATP-binding cassette transporter ABCC6 gene and ABCC6 pseudogenes in patients with pseudoxanthoma elasticum
por: Kringen, Marianne K, et al.
Publicado: (2015)

Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine
por: Adema, Auke D, et al.
Publicado: (2014)

Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo‐optico‐neuropathy (SMON)
por: Matsumoto, Hideki, et al.
Publicado: (2021)

Plasma Level of Pyrophosphate Is Low in Pseudoxanthoma Elasticum Owing to Mutations in the ABCC6 Gene, but It Does Not Correlate with ABCC6 Genotype
por: Kozák, Eszter, et al.
Publicado: (2023)

Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia
por: Flanagan, SE, et al.
Publicado: (2011)

Clinical and Metabolic Features of Adult-Onset Diabetes Caused by ABCC8 Mutations
por: Riveline, Jean-Pierre, et al.
Publicado: (2012)

Congenital hyperinsulinism: 2 case reports with different rare variants in ABCC8
por: Mouron-Hryciuk, Julie, et al.
Publicado: (2021)

Genotyping of ABCC8, KCNJ11, and HADH in Iranian Infants with Congenital Hyperinsulinism
por: Hashemian, Somayyeh, et al.
Publicado: (2021)

Glucocorticoid-Induced Hyperinsulinism in a Preterm Neonate with Inherited ABCC8 Variant
por: Motte-Signoret, Emmanuelle, et al.
Publicado: (2022)

ABCB1 and ABCC1 single-nucleotide polymorphisms in patients treated with clozapine
por: Piatkov, Irina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mh4ivhv4uob8b96sj6sgjttoa8