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Micro-RNA-195 and -451 Regulate the LKB1/AMPK Signaling Axis by Targeting MO25

BACKGROUND: Recently, MicroRNAs (miR) and AMP-kinase (AMPK) have emerged as prominent players in the development of cardiac hypertrophy and heart failure. We hypothesized that components of the adenosine monophosphate-activated kinase (AMPK) pathway are targeted by miRs and alter AMPK signaling duri...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Untiveros, Gustavo M., McKee, Laurel A. K., Perez, Jessica, Li, Jing, Antin, Parker B., Konhilas, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402395/
https://www.ncbi.nlm.nih.gov/pubmed/22844503
http://dx.doi.org/10.1371/journal.pone.0041574