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Cortical Actin Nanodynamics Determines Nitric Oxide Release in Vascular Endothelium

The release of the main vasodilator nitric oxide (NO) by the endothelial NO synthase (eNOS) is a hallmark of endothelial function. We aim at elucidating the underlying mechanism how eNOS activity depends on cortical stiffness (К(cortex)) of living endothelial cells. It is hypothesized that cortical...

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Detalles Bibliográficos
Autores principales: Fels, Johannes, Jeggle, Pia, Kusche-Vihrog, Kristina, Oberleithner, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402397/
https://www.ncbi.nlm.nih.gov/pubmed/22844486
http://dx.doi.org/10.1371/journal.pone.0041520