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Matrix-M™ Adjuvant Induces Local Recruitment, Activation and Maturation of Central Immune Cells in Absence of Antigen

Saponin-based adjuvants are widely used to enhance humoral and cellular immune responses towards vaccine antigens, although it is not yet completely known how they mediate their stimulatory effects. The aim of this study was to elucidate the mechanism of action of adjuvant Matrix-M™ without antigen...

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Detalles Bibliográficos
Autores principales: Reimer, Jenny M., Karlsson, Karin H., Lövgren-Bengtsson, Karin, Magnusson, Sofia E., Fuentes, Alexis, Stertman, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402407/
https://www.ncbi.nlm.nih.gov/pubmed/22844480
http://dx.doi.org/10.1371/journal.pone.0041451