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Matrix-M™ Adjuvant Induces Local Recruitment, Activation and Maturation of Central Immune Cells in Absence of Antigen
Saponin-based adjuvants are widely used to enhance humoral and cellular immune responses towards vaccine antigens, although it is not yet completely known how they mediate their stimulatory effects. The aim of this study was to elucidate the mechanism of action of adjuvant Matrix-M™ without antigen...
Autores principales: | Reimer, Jenny M., Karlsson, Karin H., Lövgren-Bengtsson, Karin, Magnusson, Sofia E., Fuentes, Alexis, Stertman, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402407/ https://www.ncbi.nlm.nih.gov/pubmed/22844480 http://dx.doi.org/10.1371/journal.pone.0041451 |
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