The Transcription Factor NFATp Plays a Key Role in Susceptibility to TB in Mice

In T cells, the transcription factor nuclear factor of activated T cells p (NFATp) is a key regulator of the cytokine genes tumor necrosis factor (TNF) and interferon-γ (IFN-γ). Here, we show that NFATp-deficient (NFATp(−/−)) mice have a dramatic and highly significant increase in mortality after My...

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Detalles Bibliográficos
Autores principales: Via, Laura E., Tsytsykova, Alla V., Rajsbaum, Ricardo, Falvo, James V., Goldfeld, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402414/
https://www.ncbi.nlm.nih.gov/pubmed/22844476
http://dx.doi.org/10.1371/journal.pone.0041427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402414/
https://www.ncbi.nlm.nih.gov/pubmed/22844476
http://dx.doi.org/10.1371/journal.pone.0041427

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