Removing N-Terminal Sequences in Pre-S1 Domain Enhanced Antibody and B-Cell Responses by an HBV Large Surface Antigen DNA Vaccine

Although the use of recombinant hepatitis B virus surface (HBsAg) protein vaccine has successfully reduced global hepatitis B infection, there are still a number of vaccine recipients who do not develop detectable antibody responses. Various novel vaccination approaches, including DNA vaccines, have...

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Detalles Bibliográficos
Autores principales: Ge, Guohong, Wang, Shixia, Han, Yaping, Zhang, Chunhua, Lu, Shan, Huang, Zuhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402421/
https://www.ncbi.nlm.nih.gov/pubmed/22844502
http://dx.doi.org/10.1371/journal.pone.0041573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402421/
https://www.ncbi.nlm.nih.gov/pubmed/22844502
http://dx.doi.org/10.1371/journal.pone.0041573

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