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Restoration of Corticosteroid Sensitivity by p38 Mitogen Activated Protein Kinase Inhibition in Peripheral Blood Mononuclear Cells from Severe Asthma
BACKGROUND: Severe asthma accounts for a small number of asthmatics but represents a disproportionate cost to health care systems. The underlying mechanism in severe asthma remains unknown but several mechanisms are likely to be involved because of a very heterogeneous profile. We investigated the e...
Autores principales: | Mercado, Nicolas, Hakim, Amir, Kobayashi, Yoshiki, Meah, Sally, Usmani, Omar S., Chung, Kian Fan, Barnes, Peter J., Ito, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402424/ https://www.ncbi.nlm.nih.gov/pubmed/22911818 http://dx.doi.org/10.1371/journal.pone.0041582 |
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