(Pro)renin Receptor Triggers Distinct Angiotensin II-Independent Extracellular Matrix Remodeling and Deterioration of Cardiac Function

BACKGROUND: Activation of the renin-angiotensin-system (RAS) plays a key pathophysiological role in heart failure in patients with hypertension and myocardial infarction. However, the function of (pro)renin receptor ((P)RR) is not yet solved. We determined here the direct functional and structural e...

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Detalles Bibliográficos
Autores principales: Moilanen, Anne-Mari, Rysä, Jaana, Serpi, Raisa, Mustonen, Erja, Szabò, Zoltán, Aro, Jani, Näpänkangas, Juha, Tenhunen, Olli, Sutinen, Meeri, Salo, Tuula, Ruskoaho, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402428/
https://www.ncbi.nlm.nih.gov/pubmed/22911790
http://dx.doi.org/10.1371/journal.pone.0041404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402428/
https://www.ncbi.nlm.nih.gov/pubmed/22911790
http://dx.doi.org/10.1371/journal.pone.0041404

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