A Neurotoxic Phospholipase A(2) Impairs Yeast Amphiphysin Activity and Reduces Endocytosis

BACKGROUND: Presynaptically neurotoxic phospholipases A(2) inhibit synaptic vesicle recycling through endocytosis. PRINCIPAL FINDINGS: Here we provide insight into the action of a presynaptically neurotoxic phospholipase A(2) ammodytoxin A (AtxA) on clathrin-dependent endocytosis in budding yeast. A...

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Detalles Bibliográficos
Autores principales: Mattiazzi, Mojca, Sun, Yidi, Wolinski, Heimo, Bavdek, Andrej, Petan, Toni, Anderluh, Gregor, Kohlwein, Sepp D., Drubin, David G., Križaj, Igor, Petrovič, Uroš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402474/
https://www.ncbi.nlm.nih.gov/pubmed/22844417
http://dx.doi.org/10.1371/journal.pone.0040931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402474/
https://www.ncbi.nlm.nih.gov/pubmed/22844417
http://dx.doi.org/10.1371/journal.pone.0040931

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