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A Neurotoxic Phospholipase A(2) Impairs Yeast Amphiphysin Activity and Reduces Endocytosis
BACKGROUND: Presynaptically neurotoxic phospholipases A(2) inhibit synaptic vesicle recycling through endocytosis. PRINCIPAL FINDINGS: Here we provide insight into the action of a presynaptically neurotoxic phospholipase A(2) ammodytoxin A (AtxA) on clathrin-dependent endocytosis in budding yeast. A...
Autores principales: | Mattiazzi, Mojca, Sun, Yidi, Wolinski, Heimo, Bavdek, Andrej, Petan, Toni, Anderluh, Gregor, Kohlwein, Sepp D., Drubin, David G., Križaj, Igor, Petrovič, Uroš |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402474/ https://www.ncbi.nlm.nih.gov/pubmed/22844417 http://dx.doi.org/10.1371/journal.pone.0040931 |
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