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ADP Ribosylation by PARP-1 Suppresses HOXB7 Transcriptional Activity

Interactions with cofactors regulate transcriptional activity and also help HOX proteins to achieve the specificity required for transcriptional regulation of target genes. In this study, we describe a novel protein/protein interaction of HOXB7 with poly (ADP-ribose) polymerase-1 (PARP-1) that invol...

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Detalles Bibliográficos
Autores principales: Wu, Xinyan, Ellmann, Stephan, Rubin, Ethel, Gil, Minchan, Jin, Kideok, Han, Liangfeng, Chen, Hexin, Kwon, Erika M., Guo, Jianhui, Ha, Hyo Chol, Sukumar, Saraswati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402478/
https://www.ncbi.nlm.nih.gov/pubmed/22844406
http://dx.doi.org/10.1371/journal.pone.0040644