In vivo Site-Specific Transfection of Naked Plasmid DNA and siRNAs in Mice by Using a Tissue Suction Device

We have developed an in vivo transfection method for naked plasmid DNA (pDNA) and siRNA in mice by using a tissue suction device. The target tissue was suctioned by a device made of polydimethylsiloxane (PDMS) following the intravenous injection of naked pDNA or siRNA. Transfection of pDNA encoding...

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Detalles Bibliográficos
Autores principales: Shimizu, Kazunori, Kawakami, Shigeru, Hayashi, Kouji, Kinoshita, Hideyuki, Kuwahara, Koichiro, Nakao, Kazuwa, Hashida, Mitsuru, Konishi, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402481/
https://www.ncbi.nlm.nih.gov/pubmed/22844458
http://dx.doi.org/10.1371/journal.pone.0041319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402481/
https://www.ncbi.nlm.nih.gov/pubmed/22844458
http://dx.doi.org/10.1371/journal.pone.0041319

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