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The Immunomodulatory Activity of Meningococcal Lipoprotein Ag473 Depends on the Conformation Made up of the Lipid and Protein Moieties

We have previously demonstrated that the meningococcal antigen Ag473 in the presence of Freund’s adjuvant can elicit protective immune responses in mouse challenge model. In this study, we evaluated the structural requirement for the immunological activity and the possible signaling pathway of recom...

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Detalles Bibliográficos
Autores principales: Chu, Ching-Liang, Yu, Yen-Ling, Kung, Yueh-Chen, Liao, Pei-Yu, Liu, Ko-Jiunn, Tseng, Yen-Tzu, Lin, Yuan-Chuen, Hsieh, Steve Shih-Yang, Chong, Pele Choi-Sing, Yang, Chiou-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402496/
https://www.ncbi.nlm.nih.gov/pubmed/22844415
http://dx.doi.org/10.1371/journal.pone.0040873